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Ebook [The Gene An Intimate History Siddhartha Mukherjee] zambia

Siddhartha Mukherjee ↠ 8 READ

S own family and its recurring pattern of mental illness reminding us that genetics is vitally relevant to everyday lives These concerns reverberate even urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our childrenMajestic in its ambition and unflinching in its honesty The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and futur. Thanks goes to Netgalley and a wonderful author for a wonderfully told series of stories within the world of geneticsI was worried briefly by the insistence of bringing Aristotle s take on the genome or the recapitulation of many of the grandfathers of the science such as Mendel and Darwin but the way that these otherwise well known personages were brought alive to the page was of a story than a dry recounting Even so I wasn t prepared for what was soon to comeI became engrossed in the history of American Eugenics and even so in Germany s frightful improvements all of which painted the history of the science in uite a dark and ignorant lightFortunately for all of us Crick Watson and Ferdinand come out swinging and we can see this all as a heroic step forward even considering the fact that Ferdinand never got to see her work truly recognized From here on out we ve got truly wonderful tales of Beck and the birth of recombinant DNA scientists self policing the rise of multinational bio engineering firms AIDS gene therapies genome mapping and of course cloning and stem cell blocking and each and every one of these stories are bright and very readableAnd what s it s always informative and it s always interesting It even draws us in to the author s own deep and emotional familial history and his own drive to understandI ll make no bones about it I was movedI ve read than a handful of books on genetics in the past and while some were uite good and some were sometimes mesmerizingly boring I think this one has got to be the most readable grab you on the human level and most in depth survey of the entire field that I ve ever read So many disparate characteristics managed to encode the proteins of the narrative and no one could be happier than me to see such a healthy and shining phenotypical expression be borne from a popular book It s classy and smart Very smart In fact it s pretty much a must have if you re a science history buff bringing us up to the cutting edge present and want a few uestions for the future

FREE READ The Gene An Intimate History

The Gene An Intimate History

F sexuality temperament choice and free will This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick James Watson and Rosalind Franklin and the thousands of scientists still working to understand the code of codesThis is an epic moving history of a scientific idea coming to life by the author of The Emperor of All Maladies But woven through The Gene like a red line is also an intimate history – the story of Mukherjee’. Cannot begin to tell you what I learned from this fascinating study of The Gene but I gained great insight from the thorough research of Siddhartha Mukherjee I am destined for a second readlisten The audio narration by Dennis Boutsikaris made this compelling very well paced with a distinct and pleasant tonal uality Highly recommended

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Spanning the globe and several centuries The Gene is the story of the uest to decipher the master code that makes and defines humans that governs our form and functionThe story of the gene begins in an obscure Augustinian abbey in Moravia in 1856 where a monk stumbles on the idea of a ‘unit of heredity’ It intersects with Darwin’s theory of evolution and collides with the horrors of Nazi eugenics in the 1940s The gene transforms post war biology It reorganizes our understanding o. I have this tendency when I read a book as brilliantly informing as this one to wipe the froth from my mouth shuffle the pages of notes I ve written contemporaneous to the reading and plunge into the cocktail party which is this forum grabbing each of you by the virtual lapels and launching into a lecture about one of the hundreds of things I learned in the process As if you know I missed some of the frothSo imagine me back from some journey casting pleasantries aside and launching wild eyed and yes maybe a little frothy insisting that you grasp the fraction of what I ve learned via the fraction of my ability to explain as if it is the most important thing in the world Until next week s book and next week s cocktail party that is Passionate and off putting Aware but unable to stop myself Yup that s me But I have a defenseThere s probably a gene that makes me soSeems I got than blue eyes from Mom than dark hair from Dad There are many chambers of the human heart and many caverns in the human mind but they are all there somewhere pinned onto the genome which is Tony This book is worth the read just for the section on sickle cell anemia or the one explaining the genetic basis for sexual identity or the story of Mitochondrial Eve Did you know that when the Allied forces entered the Nazi death camps they found an inordinate number of twins among the survivors This was so because Mengele was fascinated by Zwillinge These survivors sharing as they did identical genetic markers served as the subjects of much subseuent genetic research The problem with racial discrimination is not the inference of a person s race from their genetic characteristics It is uite the opposite it is the inference of a person s characteristics from their race But I ve now learned the vast proportion of genetic diversity 85 to 90 percent occurs within so called races ie within Asians or Africans and only a minor proportion 7 percent between racial groups I knew the story of Carrie Buck legally sterilized after an Opinion by Supreme Court Justice Oliver Wendell Holmes stating Three generations of imbeciles is enough But Mukherjee lets that story hover over us as he takes us to a lecture he attended in 2013 a lecture given by a fifteen year old girl named Erika who suffered from a severe progressive degenerative disease causing muscle tremors that progressively worsened She tried new drugs clinical trials Nothing worked Yet there she was speaking to this hall of scientists by far among the most articulate introspective teenagers that I have ever encountered A prenatal test to find the mutations that caused Erika s condition is theoretically possible We could bluntly prevent future Erikas Mukherjee lets us ponder this as he watches Erika being pushed by her mother across a parking lot in her wheelchair her scarf billowing behind her like an epilogueIt s that last little bit that fragment of a uote like a piece of DNA that I hope exposes why this book had such a purchase on me It s not just that Mukherjee can take a very complicated scientific subject and make it understandable It s that he does so with really gorgeous writingAt one point he is explaining how we got here how humans began on an arid mesa in South Africa and from there went west as young men often do The migrants made it to the northeastern edge of Ethiopia or Egypt where the Red Sea narrows to a slitlike strait And then he writes this There was no one there to part the ocean We do not know what drove these men and women to fling themselves across the water or how they managed to cross it What is certain is that every perilous ocean crossing left hardly any survivors perhaps as few as six hundred men and women Europeans Asians Australians and Americans are the descendants of these drastic bottlenecks and this corkscrew of history too has left its signature in our genomes In a genetic sense nearly all of us who emerged out of Africa gasping for land and air are even closely yoked than previously imagined We were on the same boat brotherThe same but different different but the same I ll stop there having no doubt expressed my enthusiasm better than my understanding of human genetics I ll stop even though the clicker below says I have 15480 characters left or about 500 less than the number of genes in one of my cells But one of the truly entertaining parts of this book was the author s use of uotes So since I m feeling epigrammy I ll add my favorites to the commentsBye I have to go


10 thoughts on “The Gene An Intimate History

  1. says:

    I have this tendency when I read a book as brilliantly informing as this one to wipe the froth from my mouth shuffle the pages of notes I've written contemporaneous to the reading and plunge into the cocktail party which is this forum grabbing each of you by the virtual lapels and launching into a lecture about one of the hundreds of things I learned in the process As if you know I missed some of the frothSo imagine me back from some journ

  2. says:

    I think this was really good and even better than The Emperor of All Maladies which I just read recently as well I might have enjoyed this one because it's relevant to my current day to day thing though I really liked the way it ties in the personal elements of genetics through out the book and how it acknowledges really important uestions of what we actually deem normal and healthy I feel like a lot of times t

  3. says:

    Hello bookish peepsAnother one of my review has been posted on our country's largest daily newspaper's website The Times o

  4. says:

    I listened to the BBC abridged audio book as I often do before ordering it I like hardbacks so I try and be sure first I want to read it I didn't like it enough I loved The Emperor of All Maladies A Biography of Cancer but couldn't feel that deep interest with this oneNow it could be that the book is fantastic and it had

  5. says:

    In this beautifully written vivid history of genetics; Mukherjee takes us by the hand and walks us through the hall of fame of all the people who are the reason for modern biology as we study it today His picturesue descriptions make the book a joy to readStarting with Mendel and ending with embryonic stem cell research and beyond; the fascinating story of genetic research is given in the book There are life stories of many exceptional scie

  6. says:

    Cannot begin to tell you what I learned from this fascinating study of The Gene but I gained great insight from the thorough researc

  7. says:

    Not half as good a narrative as The Emperor of All Maladies but still a good account of the Gene's journey and where it i

  8. says:

    Thanks goes to Netgalley and a wonderful author for a wonderfully told series of stories within the world of geneticsI was worried briefly by the insistence of bringing Aristotle's take on the genome or the recapitulation of many of the grandfathers of the science such as Mendel and Darwin but the way that thes

  9. says:

    I'm not going to lie there were some pages of this book where all my mind saw was 'science science science scienc

  10. says:

    Siddhartha Mukherjee Pulitzer's Prize winning book The Emperor of All Maladiesscared the hell out of me right from the 'get go'when I read that 1 in 4 people will get cancer in your lifetime Mukherjee dives right in again wasting no time in The Gene We first learn that mental illness has been in Mukherjee's family for at least two generations He shares personally with us about 4 different relatives 2 cousins and two uncles from h

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Tessa Young is an 18 year old college student with a simple life, excellent grades, and a sweet boyfriend She always has things planned out ahead of time, until she meets a rude boy named Harry, with too many tattoos and piercings who shatters her plans.